KLRF1, an activating homodimeric C-type lectin-like receptor (CTLR), is expressed on nearly all natural killer (NK) cells and stimulates their cytoxicity and cytokine release. KLRF1 (Killer Cell Lectin Like Receptor F1) is a Protein Coding gene. Among its related pathways are Class I MHC mediated antigen processing and presentation and Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers.