Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. The type II keratins are clustered in a region of chromosome 12q13. KRT6C (Keratin 6C) is a Protein Coding gene. Diseases associated with KRT6C include Palmoplantar Keratoderma, Nonepidermolytic, Focal Or Diffuse and Palmoplantar Keratoderma, Nonepidermolytic, Focal. Among its related pathways are Cytoskeleton remodeling Neurofilaments and Keratinization.