ID1 (Inhibitor Of DNA Binding 1, HLH Protein) is a Protein Coding gene. Diseases associated with ID1 include Salivary Gland Cancer and Multicentric Castleman Disease. Among its related pathways are Cellular Senescence (REACTOME) and TGF-B Signaling in Thyroid Cells for Epithelial-Mesenchymal Transition. The protein encoded by ID1 is a helix-loop-helix (HLH) protein that can form heterodimers with members of the basic HLH family of transcription factors. The encoded protein has no DNA binding activity and therefore can inhibit the DNA binding and transcriptional activation ability of basic HLH proteins with which it interacts. This protein may play a role in cell growth, senescence, and differentiation. Two transcript variants encoding different isoforms have been found for ID1.
