HSPB7 encodes a small heat shock family B member that can heterodimerize with similar heat shock proteins. Defects in this gene are associated with advanced heart failure. In addition, the encoded protein may be a tumor suppressor in the p53 pathway, with defects in this gene being associated with renal cell carcinoma. HSPB7 (Heat Shock Protein Family B (Small) Member 7) is a Protein Coding gene. Diseases associated with HSPB7 include Central Sleep Apnea and Systolic Heart Failure. Among its related pathways are Differentiation of white and brown adipocyte.