HASPIN (Histone H3 Associated Protein Kinase) is a Protein Coding gene. Serine/threonine-protein kinase that phosphorylates histone H3 at Thr-3 (H3T3ph) during mitosis. This positions and activates AURKB and other components of the chromosomal passenger complex (CPC) at centromeres to ensure proper chromatid cohesion, metaphase alignment and normal progression through the cell cycle.
