RASGRP3 (RAS Guanyl Releasing Protein 3) is a Protein Coding gene. Among its related pathways are RET signaling and G-protein signaling TC21 regulation pathway. GO annotations related to RASGRP3 include calcium ion binding and GTPase activator activity. The protein encoded by RASGRP3 is a guanine nucleotide exchange factor that activates the oncogenes HRAS and RAP1A. Defects in RASGRP3 have been associated with systemic lupus erythematosus and several cancers.
