Quality control in the endoplasmic reticulum (ER) ensures that only properly folded proteins are retained in the cell through recognition and degradation of misfolded or unassembled proteins. EDEM3 belongs to a group of proteins that accelerate degradation of misfolded glycoproteins in the ER. EDEM3 (ER Degradation Enhancing Alpha-Mannosidase Like Protein 3) is a Protein Coding gene. Among its related pathways are Protein processing in endoplasmic reticulum and Transport to the Golgi and subsequent modification.