DSG4 (Desmoglein 4) is a Protein Coding gene. Diseases associated with DSG4 include Hypotrichosis 6 and Monilethrix. Among its related pathways are Keratinization and Developmental Biology. DSG4 encodes a member of the desmoglein subgroup of desmosomal cadherins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a transmembrane component of desmosomes and may play a role in cell-cell adhesion in epithelial cells. Mutations in the gene are associated with localized autosomal recessive hypotrichosis and monilethrix, characterized by impaired hair growth.
