DSCAM is a member of the immunoglobulin superfamily of cell adhesion molecules (Ig-CAMs), and is involved in human central and peripheral nervous system development. DSCAM is a candidate for Down syndrome and congenital heart disease (DSCHD). A gene encoding a similar Ig-CAM protein is located on chromosome 11. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.DSCAM (DS Cell Adhesion Molecule) is a Protein Coding gene. Diseases associated with DSCAM include Down Syndrome-Related Congenital Heart Disease and Down Syndrome. Among its related pathways are Cell junction organization and Guidance Cues and Growth Cone Motility. An important paralog of this gene is DSCAML1.
