GJB5 encodes a member of the beta-type (group I) connexin family. The Gap Junction Protein Beta 5 is a gap junction protein involved in intercellular communication related to epidermal differentiation and environmental sensing. This gene has been linked to non-small cell lung cancer. GJB5 (Gap Junction Protein Beta 5) is a Protein Coding gene. Among its related pathways are Gap junction trafficking and Vesicle-mediated transport.