The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA replaces histone H3. CENPT (Centromere Protein T) is an additional factor required for centromere assembly. CENPT is a Protein Coding gene. Among its related pathways are DNA Damage and Cell Cycle, Mitotic.
