ALDH1A3 (Aldehyde Dehydrogenase 1 Family Member A3) is a Protein Coding gene. Diseases associated with ALDH1A3 include Microphthalmia, Isolated 8 and Isolated Microphthalmia. Among its related pathways are Histidine metabolism and Drug metabolism - cytochrome P450. ALDH1A3 encodes an aldehyde dehydrogenase enzyme that uses retinal as a substrate. Mutations in ALDH1A3 have been associated with microphthalmia, isolated 8, and expression changes have also been detected in tumor cells. Alternative splicing results in multiple transcript variants.
