PMEPA1（prostate transmembrane protein, androgen induced 1） encodes a transmembrane protein that contains a Smad interacting motif (SIM). Expression of PMEPA1 is induced by androgens and transforming growth factor beta, and the encoded protein suppresses the androgen receptor and transforming growth factor beta signaling pathways though interactions with Smad proteins. Overexpression of PMEPA1 may play a role in multiple types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for PMEPA1.蛋白别名为：Transmembrane prostate androgen-induced protein (Solid tumor-associated 1 protein);基因ID为：56937；蛋白质ID:Q969W9
