The protein encoded by IL17RB(interleukin 17 receptor B) is a cytokine receptor. This receptor specifically binds to IL17B and IL17E, but does not bind to IL17 and IL17C. This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E. The expression of the rat counterpart of IL17RB was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor.蛋白别名为:Interleukin-17 receptor B (IL-17 receptor B) (IL-17RB) (Cytokine receptor-like 4) (IL-17 receptor homolog 1) (IL-17Rh1) (IL17Rh1) (Interleukin-17B receptor) (IL-17B receptor);基因ID为:55540;蛋白质ID:Q9NRM6