GABRG2(gamma-aminobutyric acid type A receptor gamma2 subunit) encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in GABRG2 have been associated with epilepsy and febrile seizures. Multiple transcript variants encoding different isoforms have been identified for GABRG2.基因ID为:2566;蛋白质ID:P18507