The protein encoded by MAD2L1BP(MAD2L1 binding protein) was identified as a binding protein of the MAD2 mitotic arrest deficient-like 1 (MAD2/MAD2L1). MAD2 is a key component of the spindle checkpoint that delays the onset of anaphase until all the kinetochores are attached to the spindle. This protein may interact with the spindle checkpoint and coordinate cell cycle events in late mitosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed.蛋白别名为:MAD2L1BP; CMT2; KIAA0110; MAD2L1-binding protein; Caught by MAD2 protein;基因ID为:9587;蛋白质ID:Q15013
应用类型
WB,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, ELISA: 1:10000. Not yet tested in other applications.
免疫原
合成多肽:the N-terminal region of human MAD2L1BP. at AA rangle: 10-90