The protein encoded by CCNC(cyclin C) is a member of the cyclin family of proteins. The encoded protein interacts with cyclin-dependent kinase 8 and induces the phophorylation of the carboxy-terminal domain of the large subunit of RNA polymerase II. The level of mRNAs for this gene peaks in the G1 phase of the cell cycle. Two transcript variants encoding different isoforms have been found for CCNC.蛋白别名为:CCNC; Cyclin-C; SRB11 homolog; hSRB11;基因ID为:892;蛋白质ID:P24863
应用类型
WB,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, ELISA: 1:5000. Not yet tested in other applications.
免疫原
合成多肽:human Cyclin C around the non-phosphorylation site of S275.