The protein encoded by RELT(RELT tumor necrosis factor receptor) is a member of the TNF-receptor superfamily. This receptor is especially abundant in hematologic tissues. It has been shown to activate the NF-kappaB pathway and selectively bind TNF receptor-associated factor 1 (TRAF1). This receptor is capable of stimulating T-cell proliferation in the presence of CD3 signaling, which suggests its regulatory role in immune response. Two alternatively spliced transcript variants of RELT encoding the same protein have been reported.蛋白别名为:RELT; TNFRSF19L; Tumor necrosis factor receptor superfamily member 19L; Receptor expressed in lymphoid tissues;基因ID为:84957;蛋白质ID:Q969Z4
应用类型
WB,IHC-p,IF,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, IHC-p: 1:100-1:300, IF: 1:200-1:1000, ELISA: 1:40000. Not yet tested in other applications.
免疫原
合成多肽:the C-terminal region of human RELT. at AA rangle: 350-430