ATRIP(ATR interacting protein) encodes an essential component of the DNA damage checkpoint. The encoded protein binds to single-stranded DNA coated with replication protein A. The protein also interacts with the ataxia telangiectasia and Rad3 related protein kinase, resulting in its accumulation at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for ATRIP. 蛋白别名为:ATRIP; AGS1; ATR-interacting protein; ATM and Rad3-related-interacting protein;基因ID为:84126;蛋白质ID:Q8WXE1
应用类型
WB,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, ELISA: 1:40000. Not yet tested in other applications.
免疫原
合成多肽:human ATRIP around the phosphorylation site of S68.