Inner membrane mitochondrial proteins are responsible for the transport of metabolites across the mitochondrial membrane. SLC25A11 (Solute carrier family 25 member 11), also known as Mitochondrial 2-oxoglutarate/malate carrier protein, is a 314 amino acid multi-pass transmembrane protein belonging to the mitochondrial carrier protein family. As an oxoglutarate/malate carrier, SLC25A11 transports 2-oxoglutarate across the inner mitochondrial membrane in an electroneutral exchange for dicarboxylic acids and malate. SLC25A11 also participates in other important metabolic processes, such as the oxoglutarate/isocitrate shuttle and the malate-aspartate shuttle, as well as in nitrogen metabolism and in gluconeogenesis from lactate. SLC25A11 contains 3 solcar repeats, which is typical of substrate carrier proteins involved in energy transfer.蛋白别名为:SLC25A11; SLC20A4; Mitochondrial 2-oxoglutarate/malate carrier protein; OGCP; Solute carrier family 25 member 11;基因ID为:8402;蛋白质ID:Q02978
应用类型
WB,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, ELISA: 1:10000. Not yet tested in other applications.
免疫原
合成多肽:the Internal region of human OGCP. at AA rangle: 110-190