TCF7L1(transcription factor 7 like 1) encodes a member of the T cell factor/lymphoid enhancer factor family of transcription factors. These transcription factors are activated by beta catenin, mediate the Wnt signaling pathway and are antagonized by the transforming growth factor beta signaling pathway. The encoded protein contains a high mobility group-box DNA binding domain and participates in the regulation of cell cycle genes and cellular senescence.蛋白别名为:TCF7L1; TCF3; Transcription factor 7-like 1; HMG box transcription factor 3; TCF-3;基因ID为:83439;蛋白质ID:Q9HCS4
应用类型
WB,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, ELISA: 1:10000. Not yet tested in other applications.
免疫原
合成多肽:the Internal region of human TCF-3. at AA rangle: 290-370