RASSF7, also named as HRAS1 and HRC1, is a member of the RASSF family contain a highly conserved Ras association domain (RalGDS/AF-6 or RA) and function as Ras effectors tumor suppressors. RASSF7, RASSF8, RASSF9 and RASSF10 are four evolutionary conserved proteins that are collectively known as the N-terminal RASSF family. RASSF7 is believed to play an essential role in mitosis. RASSF7 has been shown to influence cell failure to form mitotic spindle and also cause nuclear breakdown and apoptosis. The antibody can recognizes all the 3 isoform of RASS7.蛋白别名为:RASSF7; C11orf13; HRC1; Ras association domain-containing protein 7; HRAS1-related cluster protein 1;基因ID为:8045;蛋白质ID:Q02833
应用类型
IHC-p,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: IHC-p: 1:100-1:300, ELISA: 1:5000. Not yet tested in other applications.
免疫原
合成多肽:the Internal region of human RASSF7. at AA rangle: 130-210