WEE1 (WEE1 G2 checkpoint kinase)encodes a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase.蛋白别名为:WEE1; Wee1-like protein kinase; WEE1hu; Wee1A kinase;基因ID为:7465;蛋白质ID:P30291
应用类型
IHC-p,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: IHC-p: 1:100-1:300, ELISA: 1:20000. Not yet tested in other applications.
免疫原
合成多肽:human Wee 1 around the phosphorylation site of S53.