CDK11A(cyclin dependent kinase 11A) encodes a member of the serine/threonine protein kinase family. Members of this kinase family are known to be essential for eukaryotic cell cycle control. Due to a segmental duplication, CDK11A shares very high sequence identity with a neighboring gene. These two genes are frequently deleted or altered in neuroblastoma. The protein kinase encoded by CDK11A can be cleaved by caspases and may play a role in cell apoptosis. Alternative splicing results in multiple transcript variants.蛋白别名为:CDK11A; CDC2L2; CDC2L3; PITSLREB; Cyclin-dependent kinase 11A; Cell division cycle 2-like protein kinase 2; Cell division protein kinase 11A; Galactosyltransferase-associated protein kinase p58/GTA; PITSLRE serine/threonine-protein kinase C;基因ID为:728642/984;蛋白质ID:Q9UQ88/P21127
应用类型
WB,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, ELISA: 1:10000. Not yet tested in other applications.
免疫原
合成多肽:the Internal region of human Cdk11A/B. at AA rangle: 190-270