Mutations in TSC2（tuberous sclerosis 2） lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.蛋白别名为：TSC2; TSC4; Tuberin; Tuberous sclerosis 2 protein;基因ID为：7249；蛋白质ID:P49815
应用类型
WB，IHC-p，IF，ELISA补充：最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: IHC-p: 1:100-1:300, IF: 1:200-1:1000, ELISA: 1:5000. Not yet tested in other applications.
免疫原
合成多肽：human Tuberin around the phosphorylation site of T1462.
