CLDN5 (claudin 5)encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in CLDN5 have been found in patients with velocardiofacial syndrome. Alternatively spliced transcript variants encoding the same protein have been found for CLDN5.蛋白别名为:CLDN5; AWAL; TMVCF; Claudin-5; Transmembrane protein deleted in VCFS; TMDVCF;基因ID为:7122;蛋白质ID:O00501
应用类型
IHC-p,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: IHC-p: 1:100-1:300, ELISA: 1:5000. Not yet tested in other applications.
免疫原
合成多肽:human Claudin-5 around the phosphorylation site of Y217.