The protein encoded by TH(tyrosine hydroxylase) is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in TH have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for TH.蛋白别名为:TH; TYH; Tyrosine 3-monooxygenase; Tyrosine 3-hydroxylase; TH;基因ID为:7054;蛋白质ID:P07101
应用类型
WB,IHC-p,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, IHC-p: 1:100-1:300, ELISA: 1:5000. Not yet tested in other applications.
免疫原
合成多肽:human TH around the phosphorylation site of S62.