TBX3(T-box 3) is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This protein is a transcriptional repressor and is thought to play a role in the anterior/posterior axis of the tetrapod forelimb. Mutations in TBX3 cause ulnar-mammary syndrome, affecting limb, apocrine gland, tooth, hair, and genital development. Alternative splicing of TBX3 results in three transcript variants encoding different isoforms; however, the full length nature of one variant has not been determined.蛋白别名为:TBX3; T-box transcription factor TBX3; T-box protein 3;基因ID为:6926;蛋白质ID:O15119
应用类型
WB,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, ELISA: 1:5000. Not yet tested in other applications.
免疫原
合成多肽:the Internal region of human TBX3. at AA rangle: 270-350