ZFP36L1(ZFP36 ring finger protein like 1) is a member of the TIS11 family of early response genes, which are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. ZFP36L1 is well conserved across species and has a promoter that contains motifs seen in other early-response genes. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys-his motif. This putative nuclear transcription factor most likely functions in regulating the response to growth factors. Alternatively spliced transcript variants encoding different isoforms have been found for ZFP36L1. 蛋白别名为:ZFP36L1; BERG36; BRF1; ERF1; RNF162B; TIS11B; Zinc finger protein 36; C3H1 type-like 1; Butyrate response factor 1; EGF-response factor 1; ERF-1; Protein TIS11B;基因ID为:677;蛋白质ID:Q07352
应用类型
WB,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, ELISA: 1:10000. Not yet tested in other applications.
免疫原
合成多肽:human TIS11B around the phosphorylation site of S92.