Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. MRPS24(mitochondrial ribosomal protein S24) encodes a 28S subunit protein. A pseudogene corresponding to MRPS24 is found on chromosome 11. Read-through transcription exists between MRPS24 and the upstream upregulator of cell proliferation (URGCP) gene.蛋白别名为:MRPS24; HSPC335; 28S ribosomal protein S24; mitochondrial; MRP-S24; S24mt; bMRP-47; bMRP47;基因ID为:64951;蛋白质ID:Q96EL2
应用类型
IHC-p,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: IHC-p: 1:100-1:300, ELISA: 1:40000. Not yet tested in other applications.
免疫原
合成多肽:the Internal region of human MRP-S24. at AA rangle: 30-110