TNS3, also named as TEM6, TENS1 and TPP, may play a role in actin remodeling. It is involved in the dissociation of the integrin-tensin-actin complex. EGF activates TNS4 and down-regulates TNS3 which results in capping the tail of ITGB1. TNS3 seems to be involved in mammary cell migration. It may be involved in cell migration and bone development. The antibody recognizes all the isoforms of TNS3.蛋白别名为:TNS3; TEM6; TENS1; TPP; Tensin-3; Tensin-like SH2 domain-containing protein 1; Tumor endothelial marker 6;基因ID为:64759;蛋白质ID:Q68CZ2
应用类型
IHC-p,IF,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: IHC-p: 1:100-1:300, IF: 1:200-1:1000, ELISA: 1:20000. Not yet tested in other applications.
免疫原
合成多肽:the Internal region of human Tensin3. at AA rangle: 510-590