CIDEC(cell death inducing DFFA like effector c) encodes a member of the cell death-inducing DNA fragmentation factor-like effector family. Members of this family play important roles in apoptosis. The encoded protein promotes lipid droplet formation in adipocytes and may mediate adipocyte apoptosis. CIDEC is regulated by insulin and its expression is positively correlated with insulin sensitivity. Mutations in CIDEC may contribute to insulin resistant diabetes. A pseudogene of CIDEC is located on the short arm of chromosome 3. Alternatively spliced transcript variants that encode different isoforms have been observed for CIDEC.蛋白别名为:CIDEC; FSP27; Cell death activator CIDE-3; Cell death-inducing DFFA-like effector protein C; Fat-specific protein FSP27 homolog;基因ID为:63924;蛋白质ID:Q96AQ7
应用类型
IHC-p,IF,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: IHC-p: 1:100-1:300, IF: 1:200-1:1000, ELISA: 1:5000. Not yet tested in other applications.
免疫原
合成多肽:the C-terminal region of human CIDE-3. at AA rangle: 160-240