Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. SCNN1B(sodium channel epithelial 1 beta subunit) encodes the beta subunit, and mutations in SCNN1B have been associated with pseudohypoaldosteronism type 1 (PHA1), and Liddle syndrome.蛋白别名为:SCNN1B; Amiloride-sensitive sodium channel subunit beta; Beta-NaCH; Epithelial Na(+) channel subunit beta; Beta-ENaC; ENaCB; Nonvoltage-gated sodium channel 1 subunit beta; SCNEB;基因ID为:6338;蛋白质ID:P51168
应用类型
IHC-p,IF,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: IHC-p: 1:100-1:300, IF: 1:200-1:1000, ELISA: 1:20000. Not yet tested in other applications.
免疫原
合成多肽:human ENaC β around the non-phosphorylation site of T615.