The protein encoded by PTK6（protein tyrosine kinase 6） is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of PTK6 in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of PTK6 has been detected at low levels in some breast tumors but not in normal breast tissue. The encoded protein has been shown to undergo autophosphorylation. Alternative splicing results in multiple transcript variants.蛋白别名为：PTK6; BRK; Protein-tyrosine kinase 6; Breast tumor kinase; Tyrosine-protein kinase BRK;基因ID为：5753；蛋白质ID:Q13882
应用类型
WB，IF，ELISA补充：最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, IF: 1:200-1:1000, ELISA: 1:5000. Not yet tested in other applications.
免疫原
合成多肽：human Brk around the phosphorylation site of Y447.
