The protein encoded by PRKACB(protein kinase cAMP-activated catalytic subunit beta) is a member of the serine/threonine protein kinase family. The encoded protein is a catalytic subunit of cAMP (cyclic AMP)-dependent protein kinase, which mediates signalling though cAMP. cAMP signaling is important to a number of processes, including cell proliferaton and differentiation. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.蛋白别名为:PRKACB; cAMP-dependent protein kinase catalytic subunit beta; PKA C-beta;基因ID为:5567;蛋白质ID:P22694
应用类型
WB,IHC-p,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, IHC-p: 1:100-1:300, ELISA: 1:20000. Not yet tested in other applications.
免疫原
合成多肽:the C-terminal region of human PKAβ cat. at AA rangle: 260-340