CDCA4（cell division cycle associated 4） encodes a protein that belongs to the E2F family of transcription factors. This protein regulates E2F-dependent transcriptional activation and cell proliferation, mainly through the E2F/retinoblastoma protein pathway. It also functions in the regulation of JUN oncogene expression. This protein shows distinctive nuclear-mitotic apparatus distribution, it is involved in spindle organization from prometaphase, and may also play a role as a midzone factor involved in chromosome segregation or cytokinesis. Two alternatively spliced transcript variants encoding the same protein have been noted for CDCA4. Two pseudogenes have also been identified on chromosome 1.蛋白别名为：CDCA4; HEPP; Cell division cycle-associated protein 4; Hematopoietic progenitor protein;基因ID为：55038；蛋白质ID:Q9BXL8
应用类型
IHC-p，IF，ELISA补充：最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: IHC-p: 1:100-1:300, IF: 1:200-1:1000, ELISA: 1:5000. Not yet tested in other applications.
免疫原
合成多肽：the Internal region of human CdcA4. at AA rangle: 90-170
