POLE(DNA polymerase epsilon, catalytic subunit) encodes the catalytic subunit of DNA polymerase epsilon. The enzyme is involved in DNA repair and chromosomal DNA replication. Mutations in POLE have been associated with colorectal cancer 12 and facial dysmorphism, immunodeficiency, livedo, and short stature.蛋白别名为:POLE; POLE1; DNA polymerase epsilon catalytic subunit A; DNA polymerase II subunit A;基因ID为:5426;蛋白质ID:Q07864
应用类型
IHC-p,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: IHC-p: 1:100-1:300, ELISA: 1:40000. Not yet tested in other applications.
免疫原
合成多肽:the Internal region of human DNA pol ε A. at AA rangle: 1230-1310