The protein encoded by CDKL3(cyclin dependent kinase like 3) is a member of cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. CDKL3 was identified as a gene absent in leukemic patients with chromosome 5q deletion. This loss may be an important determinant of dysmyelopoiesis. Alternative splicing results in multiple transcript variants encoding different isoforms.蛋白别名为:CDKL3; NKIAMRE; Cyclin-dependent kinase-like 3; Serine/threonine-protein kinase NKIAMRE;基因ID为:51265;蛋白质ID:Q8IVW4
应用类型
IHC-p,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: IHC-p: 1:100-1:300, ELISA: 1:5000. Not yet tested in other applications.
免疫原
合成多肽:the Internal region of human NKIAMRE. at AA rangle: 260-340