Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. MRPL51(mitochondrial ribosomal protein L51) encodes a 39S subunit protein. Pseudogenes corresponding to this gene are found on chromosomes 4p and 21q. 蛋白别名为:MRPL51; MRP64; CDA09; HSPC241; 39S ribosomal protein L51; mitochondrial; L51mt; MRP-L51; bMRP-64; bMRP64;基因ID为:51258;蛋白质ID:Q4U2R6
应用类型
WB,IHC-p,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, IHC-p: 1:100-1:300, ELISA: 1:20000. Not yet tested in other applications.
免疫原
合成多肽:the Internal region of human MRP-L51. at AA rangle: 30-110