VRK3 (vaccinia related kinase 3)encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. In both human and mouse, VRK3 has substitutions at several residues within the ATP binding motifs that in other kinases have been shown to be required for catalysis. In vitro assays indicate the protein lacks phosphorylation activity. The protein, however, likely retains its substrate binding capability. VRK3 is widely expressed in human tissues and its protein localizes to the nucleus. Alternative splicing results in multiple transcripts encoding different isoforms.蛋白别名为:VRK3; Inactive serine/threonine-protein kinase VRK3; Serine/threonine-protein pseudokinase VRK3; Vaccinia-related kinase 3;基因ID为:51231;蛋白质ID:Q8IV63
应用类型
WB,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, ELISA: 1:40000. Not yet tested in other applications.