DKK3 encodes dickkopf WNT signaling pathway inhibitor 3 that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of DKK3 is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein. 蛋白别名为:DKK3; REIC; Dickkopf-related protein 3; Dickkopf-3; Dkk-3; hDkk-3;基因ID为:27122;蛋白质ID:Q9UBP4
应用类型
WB,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, ELISA: 1:20000. Not yet tested in other applications.
免疫原
合成多肽:the Internal region of human Dkk-3. at AA rangle: 80-160