The ADP ribosylation factor GTPase activating protein 3 encoded by ARFGAP3 is a GTPase-activating protein (GAP) that associates with the Golgi apparatus and regulates the early secretory pathway of proteins. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1 (ARF1)-bound GTP, which is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is a prerequisite for the fusion of these vesicles with target compartments. The activity of this protein is sensitive to phospholipids. Multiple transcript variants encoding different isoforms have been found for this gene. ARFGAP3 was originally known as ARFGAP1, but that is now the name of a related but different gene.蛋白别名为：ARFGAP3; ARFGAP1; ADP-ribosylation factor GTPase-activating protein 3; ARF GAP 3;基因ID为：26286；蛋白质ID:Q9NP61
应用类型
WB，ELISA补充：最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, ELISA: 1:10000. Not yet tested in other applications.
免疫原
合成多肽：the Internal region of human ARF GAP3. at AA rangle: 280-360
