FDCSP encodes a small secreted protein that is expressed in follicular dendritic cells. Follicular dendritic cell secreted peptide specifically binds to activated B cells, and functions as a regulator of antibody responses. It is also thought to contribute to tumor metastases by promoting cancer cell migration and invasion.Can bind to the surface of B-lymphoma cells, but not T-lymphoma cells, consistent with a function as a secreted mediator acting upon B-cells.蛋白别名为:FDCSP; C4orf7; Follicular dendritic cell secreted peptide; FDC secreted protein; FDC-SP;基因ID为:260436;蛋白质ID:Q8NFU4
应用类型
IHC-p,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: IHC-p: 1:100-1:300, ELISA: 1:40000. Not yet tested in other applications.