The erythrocyte membrane protein band 4.1 encoded by EPB41, together with spectrin and actin, constitute the red cell membrane cytoskeletal network. This complex plays a critical role in erythrocyte shape and deformability. Mutations in this gene are associated with type 1 elliptocytosis (EL1). Alternatively spliced transcript variants encoding different isoforms have been described for this gene.蛋白别名为:EPB41; E41P; Protein 4.1; P4.1; 4.1R; Band 4.1; EPB4.1;基因ID为:2035;蛋白质ID:P11171
应用类型
WB,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, ELISA: 1:5000. Not yet tested in other applications.
免疫原
合成多肽:human 4.1R around the non-phosphorylation site of Y660.