RDM1 encodes RAD52 motif containing 1 involved in the cellular response to cisplatin, a drug commonly used in chemotherapy. The RAD52 motif containing 1 encoded by RDM1 contains two motifs: a motif found in RAD52, a protein that functions in DNA double-strand breaks and homologous recombination, and an RNA recognition motif (RRM) that is not found in RAD52. The RAD52 motif region in RAD52 is important for protein function and may be involved in DNA binding or oligomerization. Alternatively spliced transcript variants encoding different isoforms have been reported.蛋白别名为:RDM1; RAD52B; RAD52 motif-containing protein 1; RAD52 homolog B;基因ID为:201299;蛋白质ID:Q8NG50
应用类型
IHC-p,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: IHC-p: 1:100-1:300, ELISA: 1:5000. Not yet tested in other applications.
免疫原
合成多肽:the Internal region of human RDM1. at AA rangle: 90-170