CD55 encodes a glycoprotein involved in the regulation of the complement cascade. Binding of CD55 molecule (Cromer blood group) to complement proteins accelerates their decay, thereby disrupting the cascade and preventing damage to host cells. Antigens present on this protein constitute the Cromer blood group system (CROM). Alternative splicing results in multiple transcript variants. The predominant transcript variant encodes a membrane-bound protein, but alternatively spliced transcripts may produce soluble proteins. 蛋白别名为:CD55; CR; DAF; Complement decay-accelerating factor; CD antigen CD55;基因ID为:1604;蛋白质ID:P08174
应用类型
WB,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, ELISA: 1:20000. Not yet tested in other applications.
免疫原
合成多肽:the Internal region of human CD55. at AA rangle: 70-150