Fractalkine is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. CX3C chemokine receptor 1 encoded by CX3CR1 is a receptor for fractalkine. The encoded protein also is a coreceptor for HIV-1, and some variations in CX3CR1 lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. Four transcript variants encoding two different isoforms have been found for this gene.蛋白别名为:CX3CR1; CMKBRL1; GPR13; CX3C chemokine receptor 1; C-X3-C CKR-1; CX3CR1; Beta chemokine receptor-like 1; CMK-BRL-1; CMK-BRL1; Fractalkine receptor; G-protein coupled receptor 13; V28;基因ID为:1524;蛋白质ID:P49238
应用类型
IHC-p,IF,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: IHC-p: 1:100-1:300, IF: 1:200-1:1000, ELISA: 1:5000. Not yet tested in other applications.
免疫原
合成多肽:the C-terminal region of human CX3CR1. at AA rangle: 270-350