GDF7 encodes a member of the bone morphogenetic protein (BMP) family. BMPs belong to the transforming growth factor-beta superfamily of secreted signaling molecules that regulate diverse processes in growth, repair and embryonic development. The encoded preproprotein is proteolytically processed to generate the mature protein, which may play a role in the differentiation of tendon cells and spinal cord interneurons. A mutation in this gene may be associated with increased risk for Barrett's esophagus and esophageal adenocarcinoma.蛋白别名为:GDF7; Growth/differentiation factor 7; GDF-7;基因ID为:151449;蛋白质ID:Q7Z4P5
应用类型
WB,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, ELISA: 1:40000. Not yet tested in other applications.
免疫原
合成多肽:the Internal region of human GDF-7. at AA rangle: 160-240