EME1 encodes essential meiotic structure-specific endonuclease 1 that complexes with methyl methanesulfonate-sensitive UV-sensitive 81 protein to form an endonuclease complex. The encoded protein interacts with specifc DNA structures including nicked Holliday junctions, 3'-flap structures and aberrant replication fork structures. This protein may be involved in repairing DNA damage and in maintaining genomic stability. Alternative splicing results in multiple transcript variants.蛋白别名为:EME1; MMS4; Crossover junction endonuclease EME1; MMS4 homolog; hMMS4;基因ID为:146956;蛋白质ID:Q96AY2
应用类型
WB,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, ELISA: 1:5000. Not yet tested in other applications.
免疫原
合成多肽:the Internal region of human Eme1. at AA rangle: 250-330