KLF8 encodes Kruppel like factor 8 which is a member of the Sp/KLF family of transcription factors. Members of this family contain a C-terminal DNA-binding domain with three Kruppel-like zinc fingers. The Kruppel like factor 8 is thought to play an important role in the regulation of epithelial to mesenchymal transition, a process which occurs normally during development but also during metastasis. A pseudogene has been identified on chromosome 16. Alternative splicing results in multiple transcript variants. 蛋白别名为:KLF8; BKLF3; ZNF741; Krueppel-like factor 8; Basic krueppel-like factor 3; Zinc finger protein 741;基因ID为:11279;蛋白质ID:O95600
应用类型
IHC-p,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: IHC-p: 1:100-1:300, ELISA: 1:10000. Not yet tested in other applications.
免疫原
合成多肽:the Internal region of human KLF8. at AA rangle: 160-240